Control | 100 μm CBX | Wash | Control | 100 μm GZA | |
---|---|---|---|---|---|
Frequency of events (min−1) | 2.1 ± 0.2(8) | 0.5 ± 0.2**(8) | 1.4 ± 0.3(5) | 2.0 ± 0.4(4) | 1.7 ± 0.2(4) |
Baseline (F0) (a.u.) | 890 ± 109(8) | 954 ± 105(8) | 810 ± 101(5) | 875 ± 77(4) | 982 ± 109(4) |
Peak normalised amplitude (ΔF/F0) | 126 ± 25(8) | 81 ± 28*(6) | 119 ± 37(5) | 191 ± 33(4) | 160 ± 80(4) |
Decay time (s) | 4.87 ± 0.52(7) | 3.34 ± 0.35*(6) | 4.22 ± 0.21(4) | 5.45 ± 0.89(4) | 5.06 ± 0.3(4) |
Coefficient of correlation | 0.96 ± 0.01(8) | 0.66 ± 0.09**(8) | 0.73 ± 0.1(5) | 0.98 ± 0.01(4) | 0.98 ± 0.01(4) |
-
Data are expressed as mean ±s.e.m. and are sampled from neurons recorded before (control), after perfusion with carbenoxolone (CBX, 100 μm, 10 min) and wash or after glycyrrhizic acid(GZA, 100 μm, 10 min). ANOVA followed by post hoc Bonferroni's multiple comparison (CBX) or Student's unpaired t test (GZA) were applied for statistical analysis
-
↵* P < 0.05,
-
↵** P < 0.01.
-
Numbers in parentheses are the number of independent experiments.